BDBM50262471 (R)-N-(2,3-dichlorobenzyl)-N-(pyrrolidin-3-yl)isobutyramide::CHEMBL450813

SMILES CC(C)C(=O)N(Cc1cccc(Cl)c1Cl)[C@@H]1CCNC1

InChI Key InChIKey=RCMVHXAYSDWNBI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50262471   

TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50262471((R)-N-(2,3-dichlorobenzyl)-N-(pyrrolidin-3-yl)isob...)
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of [3H]DA reuptake at human dopamine transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50262471((R)-N-(2,3-dichlorobenzyl)-N-(pyrrolidin-3-yl)isob...)
Affinity DataIC50: 5nMAssay Description:Inhibition of [3H]5HT reuptake at human serotonin transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262471((R)-N-(2,3-dichlorobenzyl)-N-(pyrrolidin-3-yl)isob...)
Affinity DataIC50: 37nMAssay Description:Inhibition of [3H]NA reuptake in human noradrenaline transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed