BDBM50262468 (S)-N-(2-fluoro-4-(trifluoromethyl)benzyl)-N-(pyrrolidin-3-yl)isobutyramide::CHEMBL477584

SMILES CC(C)C(=O)N(Cc1ccc(cc1F)C(F)(F)F)[C@H]1CCNC1

InChI Key InChIKey=ZFAZBQUXCIBGID-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50262468   

TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50262468((S)-N-(2-fluoro-4-(trifluoromethyl)benzyl)-N-(pyrr...)
Affinity DataIC50: 24nMAssay Description:Inhibition of [3H]5HT reuptake at human serotonin transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262468((S)-N-(2-fluoro-4-(trifluoromethyl)benzyl)-N-(pyrr...)
Affinity DataIC50: 400nMAssay Description:Inhibition of [3H]NA reuptake in human noradrenaline transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed