BDBM50262466 (S)-N-(2,3,4-trichlorobenzyl)-N-(pyrrolidin-3-yl)isobutyramide::CHEMBL477374

SMILES CC(C)C(=O)N(Cc1ccc(Cl)c(Cl)c1Cl)[C@H]1CCNC1

InChI Key InChIKey=FFWMVMYKTQEBAE-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50262466   

TargetCytochrome P450 2D6(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50262466((S)-N-(2,3,4-trichlorobenzyl)-N-(pyrrolidin-3-yl)i...)
Affinity DataIC50: 1.76E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262466((S)-N-(2,3,4-trichlorobenzyl)-N-(pyrrolidin-3-yl)i...)
Affinity DataIC50: 6.87E+3nMAssay Description:Inhibition of human ERG potassium channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50262466((S)-N-(2,3,4-trichlorobenzyl)-N-(pyrrolidin-3-yl)i...)
Affinity DataIC50: 5.87E+3nMAssay Description:Inhibition of [3H]DA reuptake at human dopamine transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50262466((S)-N-(2,3,4-trichlorobenzyl)-N-(pyrrolidin-3-yl)i...)
Affinity DataIC50: 5nMAssay Description:Inhibition of [3H]5HT reuptake at human serotonin transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262466((S)-N-(2,3,4-trichlorobenzyl)-N-(pyrrolidin-3-yl)i...)
Affinity DataIC50: 16nMAssay Description:Inhibition of [3H]NA reuptake in human noradrenaline transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed