BDBM50262460 (S)-2-(3-((1H-indol-3-yl)methyl)morpholino)-5,5-dimethyl-5,6-dihydrobenzo[d]thiazol-7(4H)-one::CHEMBL513924

SMILES CC1(C)Cc2nc(sc2C(=O)C1)N1CCOC[C@@H]1Cc1c[nH]c2ccccc12

InChI Key InChIKey=UPQKAJYEZWCPJY-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50262460   

LigandPNGBDBM50262460((S)-2-(3-((1H-indol-3-yl)methyl)morpholino)-5,5-di...)
Affinity DataIC50: 49nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262460((S)-2-(3-((1H-indol-3-yl)methyl)morpholino)-5,5-di...)
Affinity DataIC50: 1.56E+3nMAssay Description:Inhibition of PI3K-mediated AKT Ser473 phosphorylation in PTEN negative human PC3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262460((S)-2-(3-((1H-indol-3-yl)methyl)morpholino)-5,5-di...)
Affinity DataIC50: 51nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262460((S)-2-(3-((1H-indol-3-yl)methyl)morpholino)-5,5-di...)
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibition of PI3KbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50262460((S)-2-(3-((1H-indol-3-yl)methyl)morpholino)-5,5-di...)
Affinity DataIC50: 35nMAssay Description:Inhibition of PI3KdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed