BDBM50262396 CHEMBL4102376

SMILES Cn1c(cc2c(Cl)ccnc12)-c1ccc(cc1)N1CCNCC1

InChI Key InChIKey=XULSDLWEOLKNON-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50262396   

TargetSerine/threonine-protein kinase pim-1(Human)
Sanofi Genzyme

Curated by ChEMBL
LigandPNGBDBM50262396(CHEMBL4102376)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PIM1 (unknown origin) assessed as reduction in full length human BAD phosphorylation at Ser112 residues by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Sanofi Genzyme

Curated by ChEMBL
LigandPNGBDBM50262396(CHEMBL4102376)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of PIM2 (unknown origin) assessed as reduction in full length human BAD phosphorylation at Ser112 residues by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2020
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Sanofi Genzyme

Curated by ChEMBL
LigandPNGBDBM50262396(CHEMBL4102376)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2020
Entry Details Article
PubMed
TargetCell division cycle 7-related protein kinase(Human)
Sanofi Genzyme

Curated by ChEMBL
LigandPNGBDBM50262396(CHEMBL4102376)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDC7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2020
Entry Details Article
PubMed