BDBM50262362 (S)-N-(2,4-dichlorobenzyl)-3,3-dimethyl-N-(pyrrolidin-3-yl)butanamide::CHEMBL469068

SMILES CC(C)(C)CC(=O)N(Cc1ccc(Cl)cc1Cl)[C@H]1CCNC1

InChI Key InChIKey=DINOQTNPFRDVRK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50262362   

LigandPNGBDBM50262362((S)-N-(2,4-dichlorobenzyl)-3,3-dimethyl-N-(pyrroli...)
Affinity DataIC50: 39nMAssay Description:Inhibition of [3H]NA reuptake in human noradrenaline transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50262362((S)-N-(2,4-dichlorobenzyl)-3,3-dimethyl-N-(pyrroli...)
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of [3H]DA reuptake at human dopamine transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50262362((S)-N-(2,4-dichlorobenzyl)-3,3-dimethyl-N-(pyrroli...)
Affinity DataIC50: 27nMAssay Description:Inhibition of [3H]5HT reuptake at human serotonin transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed