BDBM50262110 CHEMBL4070228

SMILES CCCCCCCCCCCCCCCCCC(=O)NC[C@H]1CC[C@@H](CC1)C(=O)N[C@@H](CCC(=O)NCCCOCCOCCOCCCNC(=O)COCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(O)=O)C(O)=O

InChI Key InChIKey=HAARGPPSVATRDO-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50262110   

TargetNeuromedin-U receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50262110(CHEMBL4070228)
Affinity DataEC50:  49nMAssay Description:Agonist activity at human NMUR1 expressed in CHO cells assessed as increase in intracellular calcium influx after 180 secs by Fluo 4-AM dye based FLI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2020
Entry Details Article
PubMed
TargetNeuromedin-U receptor 1(Mouse)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50262110(CHEMBL4070228)
Affinity DataEC50:  290nMAssay Description:Agonist activity at mouse NMUR1 expressed in CHO cells assessed as increase in intracellular calcium influx after 180 secs by Fluo 4-AM dye based FLI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2020
Entry Details Article
PubMed
TargetNeuromedin-U receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50262110(CHEMBL4070228)
Affinity DataEC50:  7.30nMAssay Description:Agonist activity at human NMUR2 expressed in CHO cells assessed as increase in intracellular calcium influx after 180 secs by Fluo 4-AM dye based FLI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2020
Entry Details Article
PubMed
TargetNeuromedin-U receptor 2(Mouse)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50262110(CHEMBL4070228)
Affinity DataEC50:  3.5nMAssay Description:Agonist activity at mouse NMUR2 expressed in CHO cells assessed as increase in intracellular calcium influx after 180 secs by Fluo 4-AM dye based FLI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2020
Entry Details Article
PubMed