BDBM50262077 CHEMBL4103826

SMILES CCCCCCCCCCCCCCCCN1CCN(CC(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N2CCC[C@H]2C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(O)=O)CC1

InChI Key InChIKey=KSLDSZRNSNAHCP-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50262077   

TargetNeuromedin-U receptor 1(Mouse)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50262077(CHEMBL4103826)
Affinity DataEC50:  70nMAssay Description:Agonist activity at mouse NMUR1 expressed in CHO cells assessed as increase in intracellular calcium influx after 180 secs by Fluo 4-AM dye based FLI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2020
Entry Details Article
PubMed
TargetNeuromedin-U receptor 2(Mouse)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50262077(CHEMBL4103826)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at mouse NMUR2 expressed in CHO cells assessed as increase in intracellular calcium influx after 180 secs by Fluo 4-AM dye based FLI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2020
Entry Details Article
PubMed
TargetNeuromedin-U receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50262077(CHEMBL4103826)
Affinity DataEC50:  3.60nMAssay Description:Agonist activity at human NMUR2 expressed in CHO cells assessed as increase in intracellular calcium influx after 180 secs by Fluo 4-AM dye based FLI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2020
Entry Details Article
PubMed
TargetNeuromedin-U receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50262077(CHEMBL4103826)
Affinity DataEC50:  42nMAssay Description:Agonist activity at human NMUR1 expressed in CHO cells assessed as increase in intracellular calcium influx after 180 secs by Fluo 4-AM dye based FLI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2020
Entry Details Article
PubMed