BDBM50262016 4-(6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-yl)quinoline::CHEMBL511563

SMILES COc1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccnc2ccccc12

InChI Key InChIKey=FAOGJKJCGFIFLI-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50262016   

TargetBone morphogenetic protein 4(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50262016(4-(6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-y...)
Affinity DataIC50: 55nMAssay Description:Inhibition of BMP4-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBone morphogenetic protein receptor type-1B(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50262016(4-(6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-y...)
Affinity DataIC50: 57nMAssay Description:Inhibition of ALK6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetActivin receptor type-1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50262016(4-(6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-y...)
Affinity DataIC50: 33nMAssay Description:Inhibition of ALK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase receptor R3(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50262016(4-(6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-y...)
Affinity DataIC50: 27nMAssay Description:Inhibition of ALK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBone morphogenetic protein receptor type-1A(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50262016(4-(6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-y...)
Affinity DataIC50: 6.80nMAssay Description:Inhibition of ALK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50262016(4-(6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-y...)
Affinity DataIC50: 3.33E+4nMAssay Description:Inhibition of ALK5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
Target5'-AMP-activated protein kinase subunit beta-1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50262016(4-(6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-y...)
Affinity DataIC50: 7.26E+3nMAssay Description:Inhibition of AMPK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetActivin receptor type-1B(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50262016(4-(6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-y...)
Affinity DataIC50: 1.84E+3nMAssay Description:Inhibition of ALK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50262016(4-(6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-y...)
Affinity DataIC50: 236nMAssay Description:Inhibition of TGFBR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed