BDBM50262014 3-[[3-(Naphthalen-1-yl)1,2,4-oxadiazole-5-carbonyl]amino]-1-[3-trifluoromethylphenyl]thiourea::CHEMBL468178

SMILES FC(F)(F)c1cccc(NC(=S)NNC(=O)c2nc(no2)-c2cccc3ccccc23)c1

InChI Key InChIKey=VKWJLJUDMWFVCW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50262014   

TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50262014(3-[[3-(Naphthalen-1-yl)1,2,4-oxadiazole-5-carbonyl...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human SIRT1 assessed as nicotinamide releasing by microplate filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50262014(3-[[3-(Naphthalen-1-yl)1,2,4-oxadiazole-5-carbonyl...)
Affinity DataIC50: 1.13E+5nMAssay Description:Inhibition of human SIRT2 assessed as nicotinamide releasing by microplate filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed