BDBM50262001 9'-(7-Hydroxy-9-oxospiro[4.5]dec-8-yl)-4',9'-dihydrospiro[cyclopentane-1,3'-xanthen]-1'(2'H)-one::CHEMBL469173

SMILES O=C1CC2(CCCC2)CC(=O)C1C1C2=C(CC3(CCCC3)CC2=O)Oc2ccccc12

InChI Key InChIKey=XVXPDHYFKLPDJW-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50262001   

TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50262001(9'-(7-Hydroxy-9-oxospiro[4.5]dec-8-yl)-4',9'-dihyd...)
Affinity DataIC50: 58nMAssay Description:Antagonist activity at human recombinant neuropeptide Y5 receptor expressed in CHO cells coexpressing Gqi5 assessed as inhibition of neuropeptide Y-i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50262001(9'-(7-Hydroxy-9-oxospiro[4.5]dec-8-yl)-4',9'-dihyd...)
Affinity DataKi:  17nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase deficient human LM cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed