BDBM50261994 2-(7-chloro-4-nitrobenzo[c][1,2,5]oxadiazol-5-ylthio)acetic acid::CHEMBL444491

SMILES OC(=O)CSc1cc(Cl)c2nonc2c1[N+]([O-])=O

InChI Key InChIKey=LEIJUUNMDKBYLE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50261994   

TargetHistone acetyltransferase GCN5(Baker's yeast)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50261994(2-(7-chloro-4-nitrobenzo[c][1,2,5]oxadiazol-5-ylth...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of Vps75-stimulated recombinant Saccharomyces cerevisiae histone acetyltransferase Rtt109 using Asf1-dH3-H4 as substrate assessed as coenz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2016
Entry Details Article
PubMed
TargetHistone acetyltransferase GCN5(Baker's yeast)
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50261994(2-(7-chloro-4-nitrobenzo[c][1,2,5]oxadiazol-5-ylth...)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of Vps75-stimulated recombinant Saccharomyces cerevisiae histone acetyltransferase Rtt109 using Asf1-dH3-H4 as substrate assessed as coenz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2016
Entry Details Article
PubMed
TargetDNA ligase 1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50261994(2-(7-chloro-4-nitrobenzo[c][1,2,5]oxadiazol-5-ylth...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human recombinant DNA ligase 1 by radioactive gel-based ligation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed