BDBM50261838 6,6-dimethyl-2-(6-(6-methylpyridin-3-yl)-2,3-dihydrobenzo[b][1,4]oxazin-4-yl)-6,7-dihydrothiazolo[5,4-c]pyridin-4(5H)-one::CHEMBL469202

SMILES Cc1ccc(cn1)-c1ccc2OCCN(c3nc4CC(C)(C)NC(=O)c4s3)c2c1

InChI Key InChIKey=MQJXZZFGKUKOGM-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50261838   

LigandPNGBDBM50261838(6,6-dimethyl-2-(6-(6-methylpyridin-3-yl)-2,3-dihyd...)
Affinity DataIC50: 21nMAssay Description:Inhibition of PI3K deltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50261838(6,6-dimethyl-2-(6-(6-methylpyridin-3-yl)-2,3-dihyd...)
Affinity DataIC50: 28nMAssay Description:Inhibition of PI3K gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50261838(6,6-dimethyl-2-(6-(6-methylpyridin-3-yl)-2,3-dihyd...)
Affinity DataIC50: 116nMAssay Description:Inhibition of PI3K alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50261838(6,6-dimethyl-2-(6-(6-methylpyridin-3-yl)-2,3-dihyd...)
Affinity DataIC50: 452nMAssay Description:Inhibition of PI3K betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50261838(6,6-dimethyl-2-(6-(6-methylpyridin-3-yl)-2,3-dihyd...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed