BDBM50261829 CHEMBL4067797

SMILES NC(=O)c1cc(Cl)c2c(Cl)c(I)n(C3CCCNCC3)c2n1

InChI Key InChIKey=LCPFTSAYXQZOCT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50261829   

TargetSerine/threonine-protein kinase pim-2(Human)
Sanofi Genzyme

Curated by ChEMBL
LigandPNGBDBM50261829(CHEMBL4067797)
Affinity DataIC50: 15nMAssay Description:Inhibition of PIM2 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Sanofi Genzyme

Curated by ChEMBL
LigandPNGBDBM50261829(CHEMBL4067797)
Affinity DataIC50: 1nMAssay Description:Inhibition of PIM1 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-3(Human)
Sanofi Genzyme

Curated by ChEMBL
LigandPNGBDBM50261829(CHEMBL4067797)
Affinity DataIC50: 3nMAssay Description:Inhibition of PIM3 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2020
Entry Details Article
PubMed