BDBM50261819 5-(4-aminophenyl)-N-(5-(hydroxyamino)-5-oxopentyl)isoxazole-3-carboxamide::CHEMBL468841

SMILES Nc1ccc(cc1)-c1cc(no1)C(=O)NCCCCC(=O)NO

InChI Key InChIKey=YOFQNKRIMRMZGL-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50261819   

TargetHistone deacetylase 1(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261819(5-(4-aminophenyl)-N-(5-(hydroxyamino)-5-oxopentyl)...)
Affinity DataIC50: 360nMAssay Description:Inhibition of HDAC1 after 17 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261819(5-(4-aminophenyl)-N-(5-(hydroxyamino)-5-oxopentyl)...)
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of HDAC2 after 17 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261819(5-(4-aminophenyl)-N-(5-(hydroxyamino)-5-oxopentyl)...)
Affinity DataIC50: 65.8nMAssay Description:Inhibition of HDAC3 after 17 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261819(5-(4-aminophenyl)-N-(5-(hydroxyamino)-5-oxopentyl)...)
Affinity DataIC50: 2.83E+3nMAssay Description:Inhibition of HDAC8 after 17 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261819(5-(4-aminophenyl)-N-(5-(hydroxyamino)-5-oxopentyl)...)
Affinity DataIC50: 35.1nMAssay Description:Inhibition of HDAC6 after 17 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261819(5-(4-aminophenyl)-N-(5-(hydroxyamino)-5-oxopentyl)...)
Affinity DataIC50: 401nMAssay Description:Inhibition of HDAC10 after 17 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed