BDBM50261818 5-(4-aminophenyl)-N-(7-(hydroxyamino)-7-oxoheptyl)isoxazole-3-carboxamide::CHEMBL467793

SMILES Nc1ccc(cc1)-c1cc(no1)C(=O)NCCCCCCC(=O)NO

InChI Key InChIKey=LPYYNHVPYNFJMU-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50261818   

TargetHistone deacetylase 1(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261818(5-(4-aminophenyl)-N-(7-(hydroxyamino)-7-oxoheptyl)...)
Affinity DataIC50: 56.3nMAssay Description:Inhibition of HDAC1 after 17 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261818(5-(4-aminophenyl)-N-(7-(hydroxyamino)-7-oxoheptyl)...)
Affinity DataIC50: 147nMAssay Description:Inhibition of HDAC2 after 17 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261818(5-(4-aminophenyl)-N-(7-(hydroxyamino)-7-oxoheptyl)...)
Affinity DataIC50: 10.2nMAssay Description:Inhibition of HDAC3 after 17 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261818(5-(4-aminophenyl)-N-(7-(hydroxyamino)-7-oxoheptyl)...)
Affinity DataIC50: 3.46E+3nMAssay Description:Inhibition of HDAC8 after 17 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261818(5-(4-aminophenyl)-N-(7-(hydroxyamino)-7-oxoheptyl)...)
Affinity DataIC50: 5.86nMAssay Description:Inhibition of HDAC6 after 17 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261818(5-(4-aminophenyl)-N-(7-(hydroxyamino)-7-oxoheptyl)...)
Affinity DataIC50: 44.9nMAssay Description:Inhibition of HDAC10 after 17 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed