BDBM50261817 CHEMBL467792::tert-butyl 4-(3-((5-(hydroxyamino)-5-oxopentyl)carbamoyl)isoxazol-5-yl)phenylcarbamate

SMILES CC(C)(C)OC(=O)Nc1ccc(cc1)-c1cc(no1)C(=O)NCCCCC(=O)NO

InChI Key InChIKey=VJBPYGRYDDJVLX-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50261817   

TargetHistone deacetylase 1(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261817(tert-butyl 4-(3-((5-(hydroxyamino)-5-oxopentyl)car...)
Affinity DataIC50: 628nMAssay Description:Inhibition of HDAC1 after 17 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261817(tert-butyl 4-(3-((5-(hydroxyamino)-5-oxopentyl)car...)
Affinity DataIC50: 1.74E+3nMAssay Description:Inhibition of HDAC2 after 17 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261817(tert-butyl 4-(3-((5-(hydroxyamino)-5-oxopentyl)car...)
Affinity DataIC50: 115nMAssay Description:Inhibition of HDAC3 after 17 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261817(tert-butyl 4-(3-((5-(hydroxyamino)-5-oxopentyl)car...)
Affinity DataIC50: 3.65E+3nMAssay Description:Inhibition of HDAC8 after 17 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261817(tert-butyl 4-(3-((5-(hydroxyamino)-5-oxopentyl)car...)
Affinity DataIC50: 31.6nMAssay Description:Inhibition of HDAC6 after 17 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261817(tert-butyl 4-(3-((5-(hydroxyamino)-5-oxopentyl)car...)
Affinity DataIC50: 690nMAssay Description:Inhibition of HDAC10 after 17 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed