BDBM50261661 CHEMBL4071600

SMILES C[C@@H](N[C@H]1CCN(C1)c1ccc(cc1)C(=O)NCCCN1CCC(CC1)C(O)=O)c1cccc2ccccc12

InChI Key InChIKey=HBTVUVNVTSSIHP-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50261661   

TargetExtracellular calcium-sensing receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50261661(CHEMBL4071600)
Affinity DataEC50:  50nMAssay Description:Agonist activity at human CaSR expressed in HEK293 cells assessed as increase in intracellular calcium mobilization by fluo-4AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2020
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Mouse)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50261661(CHEMBL4071600)
Affinity DataEC50:  251nMAssay Description:Agonist activity at mouse CaSR expressed in HEK293 cells assessed as increase in intracellular calcium mobilization by fluo-4AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2020
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50261661(CHEMBL4071600)
Affinity DataEC50:  316nMAssay Description:Agonist activity at rat CaSR expressed in HEK293 cells assessed as increase in intracellular calcium mobilization by fluo-4AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2020
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50261661(CHEMBL4071600)
Affinity DataEC50:  50nMAssay Description:Agonist activity at human CaSR expressed in HEK293 cells assessed as increase in intracellular calcium mobilization by fluo-4AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2020
Entry Details Article
PubMed