BDBM50260623 3-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-5-phenyl-4H-1,2,4-triazole::CHEMBL523177

SMILES Cn1c(nnc1C1(CCC1)c1ccc(Cl)cc1)-c1ccccc1

InChI Key InChIKey=AMRNFCHSNOKVDZ-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50260623   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50260623(3-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-5-phenyl...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human 11beta HSD1 by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50260623(3-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-5-phenyl...)
Affinity DataIC50: 52nMAssay Description:Inhibition of mouse 11beta HSD1 by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50260623(3-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-5-phenyl...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human 11beta HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50260623(3-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-5-phenyl...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of mouse 11beta HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50260623(3-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-5-phenyl...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human 11beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50260623(3-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-5-phenyl...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of mouse 11beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50260623(3-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-5-phenyl...)
Affinity DataIC50: 52nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50260623(3-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-5-phenyl...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed