BDBM50260456 CHEMBL4072513

SMILES OB(O)c1ccccc1CC(=O)N1CCC(CC1)Oc1ccc(nc1)C(F)(F)F

InChI Key InChIKey=WKPGGRWNXMVLNS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50260456   

TargetHormone-sensitive lipase(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50260456(CHEMBL4072513)
Affinity DataIC50: 810nMAssay Description:Inhibition of recombinant human HSL expressed in baculovirus infected sf9 insect cells using PNPB as substrate after 5 mins by spectrophotometric ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2020
Entry Details Article
PubMed
TargetHormone-sensitive lipase(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50260456(CHEMBL4072513)
Affinity DataIC50: 180nMAssay Description:Inhibition of HSL in rat adipocytes assessed as reduction in lipolysis by measuring glycerol concentration incubated for 30 mins by spectrophotometri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2020
Entry Details Article
PubMed