BDBM50260451 CHEMBL4082999

SMILES OB(O)c1ccccc1CC(=O)N1CCC(COc2ccc(cn2)C(F)(F)F)CC1

InChI Key InChIKey=IUWWHRXHZLAQCG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50260451   

TargetHormone-sensitive lipase(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50260451(CHEMBL4082999)
Affinity DataIC50: 260nMAssay Description:Inhibition of HSL in rat adipocytes assessed as reduction in lipolysis by measuring glycerol concentration incubated for 30 mins by spectrophotometri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2020
Entry Details Article
PubMed
TargetHormone-sensitive lipase(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50260451(CHEMBL4082999)
Affinity DataIC50: 280nMAssay Description:Inhibition of recombinant human HSL expressed in baculovirus infected sf9 insect cells using PNPB as substrate after 5 mins by spectrophotometric ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2020
Entry Details Article
PubMed