BDBM50260360 CHEMBL4103912

SMILES COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cn(C)c2ccc(F)cc12

InChI Key InChIKey=BCKIIDKDXZHTEW-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50260360   

TargetEpidermal growth factor receptor(Human)
Tsinghua University-Peking University Joint Center For Life Sciences

Curated by ChEMBL
LigandPNGBDBM50260360(CHEMBL4103912)
Affinity DataIC50: 166nMAssay Description:Inhibition of wild-type EGFR (unknown origin) using Tyr 4 peptide as substrate in presence of ATP by Z-LYTE kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Tsinghua University-Peking University Joint Center For Life Sciences

Curated by ChEMBL
LigandPNGBDBM50260360(CHEMBL4103912)
Affinity DataIC50: 166nMAssay Description:Inhibition of wild-type EGFR (unknown origin) using Tyr 4 peptide as substrate in presence of ATP by Z-LYTE kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Tsinghua University-Peking University Joint Center For Life Sciences

Curated by ChEMBL
LigandPNGBDBM50260360(CHEMBL4103912)
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin) using substrate-biotin by ELISA-based mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Tsinghua University-Peking University Joint Center For Life Sciences

Curated by ChEMBL
LigandPNGBDBM50260360(CHEMBL4103912)
Affinity DataIC50: 8.70nMAssay Description:Inhibition of wild-type EGFR (unknown origin) using substrate-biotin by ELISA-based mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Tsinghua University-Peking University Joint Center For Life Sciences

Curated by ChEMBL
LigandPNGBDBM50260360(CHEMBL4103912)
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin) using substrate-biotin by ELISA-based mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Tsinghua University-Peking University Joint Center For Life Sciences

Curated by ChEMBL
LigandPNGBDBM50260360(CHEMBL4103912)
Affinity DataIC50: 8.70nMAssay Description:Inhibition of wild-type EGFR (unknown origin) using substrate-biotin by ELISA-based mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed