BDBM50260328 CHEMBL4090675

SMILES CCc1nc2cccnc2n1Cc1ccc(\C=C\CN2CCN(CC2)C(C)C)cc1

InChI Key InChIKey=PEBXLIVSKIOKEF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50260328   

TargetG-protein coupled receptor 4(Rat)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50260328(CHEMBL4090675)
Affinity DataIC50: 2.00E+4nMAssay Description:Antagonist activity at rat GPR4 expressed in HEK cells assessed as inhibition of pH-induced cAMP accumulation preincubated for 15 mins followed by cA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2020
Entry Details Article
PubMed
TargetG-protein coupled receptor 4(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50260328(CHEMBL4090675)
Affinity DataIC50: 2.00E+4nMAssay Description:Antagonist activity at mouse GPR4 expressed in HEK cells assessed as inhibition of pH-induced cAMP accumulation preincubated for 15 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2020
Entry Details Article
PubMed
TargetG-protein coupled receptor 4(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50260328(CHEMBL4090675)
Affinity DataIC50: 9.10E+3nMAssay Description:Antagonist activity at human GPR4 expressed in African green monkey COS7 cells assessed as inhibition of pH 6.5-induced cAMP accumulation after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2020
Entry Details Article
PubMed