BDBM50260280 (S)-(4-(3-hydroxyphenyl)-1,6-dimethyl-2-thioxo-1,2,3,4-tetrahydropyrimidin-5-yl)(phenyl)methanone::CHEMBL491384

SMILES CN1C(=S)N[C@H](C(C(=O)c2ccccc2)=C1C)c1cccc(O)c1

InChI Key InChIKey=JGBBILLMZPWNFU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50260280   

TargetKinesin-like protein KIF11(Human)
Cnrs-Commissariat à

Curated by ChEMBL
LigandPNGBDBM50260280((S)-(4-(3-hydroxyphenyl)-1,6-dimethyl-2-thioxo-1,2...)
Affinity DataIC50: 520nMAssay Description:Inhibition of basal ATPase activity of human Eg5More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Cnrs-Commissariat à

Curated by ChEMBL
LigandPNGBDBM50260280((S)-(4-(3-hydroxyphenyl)-1,6-dimethyl-2-thioxo-1,2...)
Affinity DataIC50: 650nMAssay Description:Inhibition of microtubule-stimulated human Eg5 ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Cnrs-Commissariat à

Curated by ChEMBL
LigandPNGBDBM50260280((S)-(4-(3-hydroxyphenyl)-1,6-dimethyl-2-thioxo-1,2...)
Affinity DataIC50: 520nMAssay Description:Inhibition of Eg5 assessed as inhibition of microtubule-induced ATPase activity (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Cnrs-Commissariat à

Curated by ChEMBL
LigandPNGBDBM50260280((S)-(4-(3-hydroxyphenyl)-1,6-dimethyl-2-thioxo-1,2...)
Affinity DataIC50: 150nMAssay Description:Inhibition of Eg5 basal ATPase activity (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed