BDBM50260228 CHEMBL489344::N-methyl-4-(2-(piperidin-4-yl)-5-(3-(trifluoromethyl)phenyl)-1H-imidazol-4-yl)pyrimidin-2-amine

SMILES CNc1nccc(n1)-c1nc([nH]c1-c1cccc(c1)C(F)(F)F)C1CCNCC1

InChI Key InChIKey=RHBGODQVOKDULK-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50260228   

TargetCasein kinase I isoform delta(Human)
Istituto Di Ricerche Di Biologia Molecolare &Quot;P. Angeletti

Curated by ChEMBL
LigandPNGBDBM50260228(N-methyl-4-(2-(piperidin-4-yl)-5-(3-(trifluorometh...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human CKIdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCasein kinase I isoform alpha(Human)
Istituto Di Ricerche Di Biologia Molecolare &Quot;P. Angeletti

Curated by ChEMBL
LigandPNGBDBM50260228(N-methyl-4-(2-(piperidin-4-yl)-5-(3-(trifluorometh...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human CKIalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Istituto Di Ricerche Di Biologia Molecolare &Quot;P. Angeletti

Curated by ChEMBL
LigandPNGBDBM50260228(N-methyl-4-(2-(piperidin-4-yl)-5-(3-(trifluorometh...)
Affinity DataIC50: 3.85E+5nMAssay Description:Inhibition of human JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Istituto Di Ricerche Di Biologia Molecolare &Quot;P. Angeletti

Curated by ChEMBL
LigandPNGBDBM50260228(N-methyl-4-(2-(piperidin-4-yl)-5-(3-(trifluorometh...)
Affinity DataIC50: 4.04E+5nMAssay Description:Inhibition of human JNK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-3(Human)
Istituto Di Ricerche Di Biologia Molecolare &Quot;P. Angeletti

Curated by ChEMBL
LigandPNGBDBM50260228(N-methyl-4-(2-(piperidin-4-yl)-5-(3-(trifluorometh...)
Affinity DataIC50: 7.60E+4nMAssay Description:Inhibition of human RSK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Istituto Di Ricerche Di Biologia Molecolare &Quot;P. Angeletti

Curated by ChEMBL
LigandPNGBDBM50260228(N-methyl-4-(2-(piperidin-4-yl)-5-(3-(trifluorometh...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human CK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed