BDBM50260149 CHEMBL4074476

SMILES Fc1ccc(cc1C(=O)NCCc1cccnc1)[C@@H]1CCNC[C@H]1COc1ccc2OCOc2c1

InChI Key InChIKey=XSLTVZFFDLTMDZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50260149   

TargetG protein-coupled receptor kinase 5(Bovine)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50260149(CHEMBL4074476)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of bovine GRK5 after 5 mins after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetRhodopsin kinase GRK1(Bovine)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50260149(CHEMBL4074476)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of bovine GRK1 (1 to 535 residues) after 5 mins after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetBeta-adrenergic receptor kinase 1(Bovine)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50260149(CHEMBL4074476)
Affinity DataIC50: 3.02E+3nMAssay Description:Inhibition of bovine GRK2 S670A mutant after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed