BDBM50260009 CHEMBL4077561

SMILES CCc1ccc(cc1C#Cc1ccc2ccnn2c1)C(=O)Nc1cc(CN2CCN(C)CC2)cc(c1)C(F)(F)F

InChI Key InChIKey=DRNRCLNUHIQXOJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50260009   

TargetEpithelial discoidin domain-containing receptor 1(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50260009(CHEMBL4077561)
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human GST-tagged DDR1 catalytic domain expressed in baculovirus expression system using Fluorescein-Poly GAT as substrate m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2020
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50260009(CHEMBL4077561)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of recombinant human His-tagged c-kit cytoplasmic domain (544 to 976 residues) expressed in baculovirus expression system using Ser/Thr 6 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2020
Entry Details Article
PubMed
TargetDiscoidin domain-containing receptor 2(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50260009(CHEMBL4077561)
Affinity DataIC50: 203nMAssay Description:Inhibition of recombinant human GST-tagged DDR2 cytoplasmic domain expressed in baculovirus expression system using Fluorescein-Poly GAT as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2020
Entry Details Article
PubMed
LigandPNGBDBM50260009(CHEMBL4077561)
Affinity DataIC50: 414nMAssay Description:Inhibition of recombinant human full length His-tagged Bcr-Abl fusion protein cytoplasmic domain expressed in baculovirus expression system using tyr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2020
Entry Details Article
PubMed