BDBM50259907 CHEMBL4101747

SMILES CC(C)c1nc(N)n2CCCC(Cc3cccc4OCOc34)c12

InChI Key InChIKey=VDCLREYSLXKWQN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50259907   

TargetPolycomb protein EED(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50259907(CHEMBL4101747)
Affinity DataIC50: 430nMAssay Description:Binding affinity to human methionine-13Cepsilon-methyl labeled PRC2-EED (76 to 441 residues) expressed in Escherichia coli BL21 (DE3) by 2D NMR metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed
TargetPolycomb protein EED(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50259907(CHEMBL4101747)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of EED in human G401 cells assessed as reduction in H3K27 methylation measured after 48 hrs by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMed