BDBM50259746 (4-Hydroxyphenyl)ethyl trans-ferulate::CHEMBL481245::p-Hydroxyphenethyl trans-ferulate (18)::p-hydroxyphenethyl trans-ferulate

SMILES COc1cc(\C=C\C(=O)OCCc2ccc(O)cc2)ccc1O

InChI Key InChIKey=JMSFLLZUCIXALN-UHFFFAOYSA-N

Data  12 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50259746   

TargetPancreatic triacylglycerol lipase(Pig)
Seoul National University

LigandPNGBDBM50259746(p-hydroxyphenethyl trans-ferulate | (4-Hydroxyphen...)
Affinity DataIC50: 5.00E+4nMpH: 7.4 T: 2°CAssay Description:Various concentrations of test compound (5, 10, 25, 50 and 100 mM) were dissolved in DMSO (final culture concentration 0.1%) and 4-MU oleate and lipa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50259746(p-hydroxyphenethyl trans-ferulate | (4-Hydroxyphen...)
Affinity DataIC50: 4.76E+4nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
University of Louisiana At Monroe

Curated by ChEMBL
LigandPNGBDBM50259746(p-hydroxyphenethyl trans-ferulate | (4-Hydroxyphen...)
Affinity DataIC50: 1.29E+4nMAssay Description:Inhibition of recombinant human N-terminal His-tagged cytoplasmic c-MET kinase domain (956 to 1390 residues) phosphorylation expressed in baculovirus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50259746(p-hydroxyphenethyl trans-ferulate | (4-Hydroxyphen...)
Affinity DataKi:  620nMAssay Description:Inhibition of human carbonic anhydrase 7 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 5B, mitochondrial(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50259746(p-hydroxyphenethyl trans-ferulate | (4-Hydroxyphen...)
Affinity DataKi:  670nMAssay Description:Inhibition of human carbonic anhydrase 5B preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 14(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50259746(p-hydroxyphenethyl trans-ferulate | (4-Hydroxyphen...)
Affinity DataKi:  720nMAssay Description:Inhibition of human carbonic anhydrase 14 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50259746(p-hydroxyphenethyl trans-ferulate | (4-Hydroxyphen...)
Affinity DataKi:  770nMAssay Description:Inhibition of human carbonic anhydrase 6 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50259746(p-hydroxyphenethyl trans-ferulate | (4-Hydroxyphen...)
Affinity DataKi:  810nMAssay Description:Inhibition of human catalytic domain of carbonic anhydrase 9 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 5A, mitochondrial(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50259746(p-hydroxyphenethyl trans-ferulate | (4-Hydroxyphen...)
Affinity DataKi:  810nMAssay Description:Inhibition of human carbonic anhydrase 5A preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 13(Mouse)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50259746(p-hydroxyphenethyl trans-ferulate | (4-Hydroxyphen...)
Affinity DataKi:  930nMAssay Description:Inhibition of mouse carbonic anhydrase 13 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50259746(p-hydroxyphenethyl trans-ferulate | (4-Hydroxyphen...)
Affinity DataKi:  8.47E+3nMAssay Description:Inhibition of human catalytic domain of carbonic anhydrase 12 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50259746(p-hydroxyphenethyl trans-ferulate | (4-Hydroxyphen...)
Affinity DataKi:  4.40E+4nMAssay Description:Inhibition of human carbonic anhydrase 4 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 3(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50259746(p-hydroxyphenethyl trans-ferulate | (4-Hydroxyphen...)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human carbonic anhydrase 3 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50259746(p-hydroxyphenethyl trans-ferulate | (4-Hydroxyphen...)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50259746(p-hydroxyphenethyl trans-ferulate | (4-Hydroxyphen...)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed