BDBM50259603 CHEMBL4087723

SMILES FC(F)(F)c1cc(=O)oc2cc(OCc3ccc(Br)cc3)ccc12

InChI Key InChIKey=OYQVJRKBTAURET-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50259603   

TargetAcetylcholinesterase(Electric eel)
University of The Western Cape

Curated by ChEMBL
LigandPNGBDBM50259603(CHEMBL4087723)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured after 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
University of The Western Cape

Curated by ChEMBL
LigandPNGBDBM50259603(CHEMBL4087723)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human MAO-A assessed as reduction in 4-hydroxyquinolone production using kynuramine as substrate after 20 mins by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed
TargetCholinesterase(Horse)
University of The Western Cape

Curated by ChEMBL
LigandPNGBDBM50259603(CHEMBL4087723)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of equine serum BuChE using S-butylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of The Western Cape

Curated by ChEMBL
LigandPNGBDBM50259603(CHEMBL4087723)
Affinity DataIC50: 104nMAssay Description:Inhibition of recombinant human MAO-B assessed as reduction in 4-hydroxyquinolone production using kynuramine as substrate after 20 mins by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50259603(CHEMBL4087723)
Affinity DataIC50: 750nMAssay Description:Binding affinity to GST-tagged AR ligand binding domain (unknown origin) measured after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50259603(CHEMBL4087723)
Affinity DataIC50: 170nMAssay Description:Inhibition of AR transcriptional activity in human LNCaP cells harboring ARR2PB-eGFP incubated for 72 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50259603(CHEMBL4087723)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at glucocorticoid receptor in human HeLa cells assessed as reduction in dexamethasone-induced luciferase activity by dual-Glo luc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed