BDBM50259509 (2S,3S,3aR,9bR)-2-(4-benzylpiperidine-1-carbonyl)-3-(hydroxymethyl)-1-(4-phenoxybenzyl)-2,3,3a,4-tetrahydro-1H-pyrrolo[2,3-a]indolizin-6(9bH)-one::CHEMBL509472

SMILES OC[C@H]1[C@@H]2Cn3c(cccc3=O)[C@@H]2N(Cc2ccc(Oc3ccccc3)cc2)[C@@H]1C(=O)N1CCC(Cc2ccccc2)CC1

InChI Key InChIKey=UQBOWGUWBXERMG-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50259509   

TargetApoptosis regulator Bcl-2(Human)
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50259509((2S,3S,3aR,9bR)-2-(4-benzylpiperidine-1-carbonyl)-...)
Affinity DataKi:  5.20E+3nMAssay Description:Displacement of fluorescently-tagged BH3 peptide from Bcl-2 by chemiluminescent nitrogen detection methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50259509((2S,3S,3aR,9bR)-2-(4-benzylpiperidine-1-carbonyl)-...)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of fluorescently-tagged BH3 peptide from Bcl-XL by chemiluminescent nitrogen detection methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed