BDBM50259354 CHEMBL4090223

SMILES CSc1ccc2ncc(-c3ccc4[nH]ccc4c3)n2n1

InChI Key InChIKey=XNYOTZHBHJIMBV-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50259354   

TargetDual specificity protein kinase CLK2(Mouse)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50259354(CHEMBL4090223)
Affinity DataIC50: 220nMAssay Description:Inhibition of GST tagged recombinant mouse CLK2 expressed in Escherichia coli using RS peptide as substrate after 30 mins by [gamma-33P]ATP based sci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2020
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK4(Mouse)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50259354(CHEMBL4090223)
Affinity DataIC50: 92nMAssay Description:Inhibition of GST tagged recombinant mouse CLK4 expressed in Escherichia coli using RS peptide as substrate after 30 mins by [gamma-33P]ATP based sci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2020
Entry Details Article
PubMed
LigandPNGBDBM50259354(CHEMBL4090223)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of GST tagged recombinant human DYRK1B expressed in Escherichia coli using woodtide as substrate after 30 mins by [gamma-33P]ATP based sci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2020
Entry Details Article
PubMed
LigandPNGBDBM50259354(CHEMBL4090223)
Affinity DataIC50: 580nMAssay Description:Inhibition of GST tagged recombinant human DYRK1A expressed in Escherichia coli using woodtide as substrate after 30 mins by [gamma-33P]ATP based sci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2020
Entry Details Article
PubMed
LigandPNGBDBM50259354(CHEMBL4090223)
Affinity DataIC50: 440nMAssay Description:Inhibition of GST tagged recombinant human DYRK2 expressed in Escherichia coli using using woodtide as substrate after 30 mins by [gamma-33P]ATP base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2020
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK3(Mouse)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50259354(CHEMBL4090223)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of GST tagged recombinant mouse CLK3 expressed in Escherichia coli using RS peptide as substrate after 30 mins by [gamma-33P]ATP based sci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2020
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Mouse)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50259354(CHEMBL4090223)
Affinity DataIC50: 130nMAssay Description:Inhibition of GST tagged recombinant mouse CLK1 expressed in Escherichia coli using RS peptide as substrate after 30 mins by [gamma-33P]ATP based sci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2020
Entry Details Article
PubMed
LigandPNGBDBM50259354(CHEMBL4090223)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of GST tagged recombinant human DYRK3 expressed in Escherichia coli using woodtide as substrate after 30 mins by [gamma-33P]ATP based scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2020
Entry Details Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50259354(CHEMBL4090223)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human recombinant CDK9/cyclin T expressed in insect cells using CDK7/9-tide as substrate after 30 mins by [gamma-33P]ATP based scintill...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2020
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50259354(CHEMBL4090223)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of human recombinant CDK5/p25 after 30 mins by [gamma-33P]ATP based scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2020
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50259354(CHEMBL4090223)
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of human recombinant CDK2/cyclin A after 30 mins by [gamma-33P]ATP based scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2020
Entry Details Article
PubMed