BDBM50259177 CHEMBL466674::N-(3-(4-chloro-3-(trifluoromethyl)benzyl)-4-oxo-3,4-dihydroquinazolin-6-yl)-2-hydroxyacetamide

SMILES OCC(=O)Nc1ccc2ncn(Cc3ccc(Cl)c(c3)C(F)(F)F)c(=O)c2c1

InChI Key InChIKey=IDYGCGYCHOUWQB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50259177   

TargetStearoyl-CoA desaturase(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50259177(N-(3-(4-chloro-3-(trifluoromethyl)benzyl)-4-oxo-3,...)
Affinity DataIC50: 110nMAssay Description:Inhibition of delta-(9)-desaturase from human HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Rat)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50259177(N-(3-(4-chloro-3-(trifluoromethyl)benzyl)-4-oxo-3,...)
Affinity DataIC50: 190nMAssay Description:Inhibition of rat microsomal delta-(9)-desaturaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Rat)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50259177(N-(3-(4-chloro-3-(trifluoromethyl)benzyl)-4-oxo-3,...)
Affinity DataIC50: 190nMAssay Description:Inhibition of stearoyl-CoA delta9 desaturase in rat microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50259177(N-(3-(4-chloro-3-(trifluoromethyl)benzyl)-4-oxo-3,...)
Affinity DataIC50: 110nMAssay Description:Inhibition of stearoyl-CoA delta9 desaturase in human HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed