BDBM50259175 CHEMBL444433::N-(3-(3,4-dichlorobenzyl)-4-oxo-3,4-dihydroquinazolin-6-yl)-2-hydroxyacetamide

SMILES OCC(=O)Nc1ccc2ncn(Cc3ccc(Cl)c(Cl)c3)c(=O)c2c1

InChI Key InChIKey=ZZCPRLFJMWBCSV-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50259175   

TargetAcyl-CoA (8-3)-desaturase(Mouse)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50259175(N-(3-(3,4-dichlorobenzyl)-4-oxo-3,4-dihydroquinazo...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of delta-(5)-desaturase in mouse ABMC7 cells by high throughput radioassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcyl-CoA 6-desaturase(Mouse)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50259175(N-(3-(3,4-dichlorobenzyl)-4-oxo-3,4-dihydroquinazo...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of delta-(6)-desaturase in mouse ABMC7 cells by high throughput radioassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Rat)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50259175(N-(3-(3,4-dichlorobenzyl)-4-oxo-3,4-dihydroquinazo...)
Affinity DataIC50: 261nMAssay Description:Inhibition of rat microsomal delta-(9)-desaturaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Rat)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50259175(N-(3-(3,4-dichlorobenzyl)-4-oxo-3,4-dihydroquinazo...)
Affinity DataIC50: 261nMAssay Description:Inhibition of stearoyl-CoA delta9 desaturase in rat microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50259175(N-(3-(3,4-dichlorobenzyl)-4-oxo-3,4-dihydroquinazo...)
Affinity DataIC50: 119nMAssay Description:Inhibition of stearoyl-CoA delta9 desaturase in human HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Rat)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50259175(N-(3-(3,4-dichlorobenzyl)-4-oxo-3,4-dihydroquinazo...)
Affinity DataIC50: 2.61E+5nMAssay Description:Inhibition of rat SCD1 by rat microsomal assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed