BDBM50258822 4-(4-methyl-1H-indol-5-ylamino)-5-(4-(2-(4-methylpiperazin-1-yl)ethoxy)phenyl)nicotinonitrile::CHEMBL467069

SMILES CN1CCN(CCOc2ccc(cc2)-c2cncc(C#N)c2Nc2ccc3[nH]ccc3c2C)CC1

InChI Key InChIKey=LTGPAFCQBMWTBC-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50258822   

TargetProtein kinase C eta type(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50258822(4-(4-methyl-1H-indol-5-ylamino)-5-(4-(2-(4-methylp...)
Affinity DataIC50: 450nMAssay Description:Inhibition of human PKCeta by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProtein kinase C theta type(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50258822(4-(4-methyl-1H-indol-5-ylamino)-5-(4-(2-(4-methylp...)
Affinity DataIC50: 7.40nMAssay Description:Inhibition of human PKCtheta by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProtein kinase C delta type(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50258822(4-(4-methyl-1H-indol-5-ylamino)-5-(4-(2-(4-methylp...)
Affinity DataIC50: 51nMAssay Description:Inhibition of human PKCdelta by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProtein kinase C beta type(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50258822(4-(4-methyl-1H-indol-5-ylamino)-5-(4-(2-(4-methylp...)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of human PKCbeta by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProtein kinase C epsilon type(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50258822(4-(4-methyl-1H-indol-5-ylamino)-5-(4-(2-(4-methylp...)
Affinity DataIC50: 54nMAssay Description:Inhibition of human PKCepsilon by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProtein kinase C zeta type(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50258822(4-(4-methyl-1H-indol-5-ylamino)-5-(4-(2-(4-methylp...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PKCzeta by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lyn(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50258822(4-(4-methyl-1H-indol-5-ylamino)-5-(4-(2-(4-methylp...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of LynMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50258822(4-(4-methyl-1H-indol-5-ylamino)-5-(4-(2-(4-methylp...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50258822(4-(4-methyl-1H-indol-5-ylamino)-5-(4-(2-(4-methylp...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50258822(4-(4-methyl-1H-indol-5-ylamino)-5-(4-(2-(4-methylp...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ROCK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProtein kinase C theta type(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50258822(4-(4-methyl-1H-indol-5-ylamino)-5-(4-(2-(4-methylp...)
Affinity DataIC50: 7.40nMAssay Description:Inhibition of PKCthetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProtein kinase C delta type(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50258822(4-(4-methyl-1H-indol-5-ylamino)-5-(4-(2-(4-methylp...)
Affinity DataIC50: 51nMAssay Description:Inhibition of PKCdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed