BDBM50258812 CHEMBL468297::N-cyclopropyl-3-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-6-amine

SMILES C1CC1Nc1ccc2nnc(-c3ccccc3)n2n1

InChI Key InChIKey=RCJWOHKIDMXOTM-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50258812   

TargetSerine/threonine-protein kinase pim-1(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50258812(N-cyclopropyl-3-phenyl-[1,2,4]triazolo[4,3-b]pyrid...)
Affinity DataKi:  1.80E+3nMAssay Description:Inhibition of Pim1 assessed as [32P] incorporation preincubated for 15 mins before ATP substrate addition by coupled spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed