BDBM50258672 CHEMBL513681::[4-(2,3,4,5-Tetrahydro-1,3-dimethyl-2,4-dioxo-1H-pyrrolo[3,2-d]pyrimidin-6-yl)phenyl]methyl thiophen-3-ylcarbamate

SMILES Cn1c2cc([nH]c2c(=O)n(C)c1=O)-c1ccc(COC(=O)Nc2ccsc2)cc1

InChI Key InChIKey=CRYQUEMGJRNSNJ-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50258672   

TargetAdenosine receptor A2b(Human)
Universidade Estadual De Feira De Santana

Curated by ChEMBL
LigandPNGBDBM50258672([4-(2,3,4,5-Tetrahydro-1,3-dimethyl-2,4-dioxo-1H-p...)
Affinity DataKi:  0.794nMAssay Description:Antagonist activity at Adenosine receptor subtype 2B in human RBC assessed as change in erythrocyte morphology incubated for 3 hrs with occasional ge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Universidade Estadual De Feira De Santana

Curated by ChEMBL
LigandPNGBDBM50258672([4-(2,3,4,5-Tetrahydro-1,3-dimethyl-2,4-dioxo-1H-p...)
Affinity DataKi:  0.800nMAssay Description:Displacement of [3H]DPCPX from human recombinant adenosine A2B receptor expressed in HEK293 cells by beta scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Universidade De Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50258672([4-(2,3,4,5-Tetrahydro-1,3-dimethyl-2,4-dioxo-1H-p...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]DPCPX from human recombinant adenosine A1 receptor expressed in CHO cells by beta scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Universidade De Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50258672([4-(2,3,4,5-Tetrahydro-1,3-dimethyl-2,4-dioxo-1H-p...)
Affinity DataKi:  10.5nMAssay Description:Displacement of [3H]ZM241385 from human recombinant adenosine A2A receptor expressed in HeLa cells by beta scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Universidade De Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50258672([4-(2,3,4,5-Tetrahydro-1,3-dimethyl-2,4-dioxo-1H-p...)
Affinity DataKi:  363nMAssay Description:Displacement of [3H]NECA from human recombinant adenosine A3 receptor expressed in HeLa cells by beta scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed