BDBM50258597 CHEMBL4061509

SMILES COc1cccc(c1)-c1cc(ccn1)C(=O)N1CCN(Cc2ccc(Cl)cc2)CC1

InChI Key InChIKey=ZWVXOQTXNTYSIG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50258597   

TargetSerine/threonine-protein kinase WNK1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50258597(CHEMBL4061509)
Affinity DataIC50: 971nMAssay Description:Allosteric inhibition of WNK1 (unknown origin) expressed in HEK293 cells co-expressing flag-OSR1 assessed as reduction in sorbitol-stimulated OSR1 ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details Article
PubMed