BDBM50258417 (+/-)-N-(3-(3'H-spiro[cyclohexane-1,1'-isobenzofuran]-4-yl)propyl)-2-(3,4-difluorophenyl)-N-methyl-2-(1H-pyrazol-1-yl)acetamide::CHEMBL493962

SMILES CN(CCCC1CCC2(CC1)OCc1ccccc21)C(=O)C(c1ccc(F)c(F)c1)n1cccn1

InChI Key InChIKey=ZDWRWVXWVHMQNH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50258417   

TargetMelanin-concentrating hormone receptor 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50258417((+/-)-N-(3-(3'H-spiro[cyclohexane-1,1'-isobenzofur...)
Affinity DataIC50: 1.70nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50258417((+/-)-N-(3-(3'H-spiro[cyclohexane-1,1'-isobenzofur...)
Affinity DataIC50: 3.60E+3nMAssay Description:Displacement of [3H]prazosin from human adrenergic alpha1A receptor expressed in thymidine kinase-deficient mouse LM cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed