BDBM50258404 6-((3',5'-dichlorobiphenyl-3-yl)methylamino)-9-(3-hydroxypropyl)-9H-purine-2-carbonitrile::CHEMBL495016

SMILES OCCCn1cnc2c(NCc3cccc(c3)-c3cc(Cl)cc(Cl)c3)nc(nc12)C#N

InChI Key InChIKey=BABOXQWWOWUXJX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50258404   

TargetCathepsin B(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50258404(6-((3',5'-dichlorobiphenyl-3-yl)methylamino)-9-(3-...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human liver cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetProcathepsin L(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50258404(6-((3',5'-dichlorobiphenyl-3-yl)methylamino)-9-(3-...)
Affinity DataIC50: 900nMAssay Description:Inhibition of human liver cathepsin LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University of California

Curated by ChEMBL
LigandPNGBDBM50258404(6-((3',5'-dichlorobiphenyl-3-yl)methylamino)-9-(3-...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed