BDBM50258388 5-(4-(2-(2-(dimethylamino)ethylamino)ethoxy)phenyl)-4-(4-methyl-1H-indol-5-ylamino)nicotinonitrile::CHEMBL494166

SMILES CN(C)CCNCCOc1ccc(cc1)-c1cncc(C#N)c1Nc1ccc2[nH]ccc2c1C

InChI Key InChIKey=ZRTHIYZKVPIBMW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50258388   

TargetProtein kinase C theta type(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50258388(5-(4-(2-(2-(dimethylamino)ethylamino)ethoxy)phenyl...)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of human PKCtheta by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProtein kinase C delta type(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50258388(5-(4-(2-(2-(dimethylamino)ethylamino)ethoxy)phenyl...)
Affinity DataIC50: 18nMAssay Description:Inhibition of human PKCdelta by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed