BDBM50258344 4-(4-methyl-1H-indol-5-ylamino)-5-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)nicotinonitrile::CHEMBL494412

SMILES Cc1c(Nc2c(cncc2-c2ccc(OCCN3CCCC3)cc2)C#N)ccc2[nH]ccc12

InChI Key InChIKey=KJYFFRNQSIBKHB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50258344   

TargetProtein kinase C theta type(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50258344(4-(4-methyl-1H-indol-5-ylamino)-5-(4-(2-(pyrrolidi...)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of human PKCtheta by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProtein kinase C delta type(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50258344(4-(4-methyl-1H-indol-5-ylamino)-5-(4-(2-(pyrrolidi...)
Affinity DataIC50: 28nMAssay Description:Inhibition of human PKCdelta by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed