BDBM50258298 1-(3-(3-methoxyphenyl)-5-sulfamoyl-1H-indole-2-carboxamido)-2,4,6-trimethylpyridinium perchlorate::1-({[5-(Aminosulfonyl)-3-(3-methoxyphenyl)-1H-indol-2-yl]carbonyl}amino)-2,4,6 trimethylpyridinium perchlorate::CHEMBL521690

SMILES COc1cccc(c1)-c1c([nH]c2ccc(cc12)S(N)(=O)=O)C(=O)N[n+]1c(C)cc(C)cc1C

InChI Key InChIKey=UYUBFBWOFKSJPT-UHFFFAOYSA-O

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50258298   

TargetCarbonic anhydrase 1(Human)
Istanbul University

Curated by ChEMBL
LigandPNGBDBM50258298(1-({[5-(Aminosulfonyl)-3-(3-methoxyphenyl)-1H-indo...)
Affinity DataKi:  0.920nMAssay Description:Inhibition of human recombinant CA1 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Istanbul University

Curated by ChEMBL
LigandPNGBDBM50258298(1-({[5-(Aminosulfonyl)-3-(3-methoxyphenyl)-1H-indo...)
Affinity DataKi:  1.80nMAssay Description:Inhibition of human recombinant CA2 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBeta-carbonic anhydrase 1(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Istanbul University

Curated by ChEMBL
LigandPNGBDBM50258298(1-({[5-(Aminosulfonyl)-3-(3-methoxyphenyl)-1H-indo...)
Affinity DataKi:  8.60nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant carbonic anhydrase Rv1284 by by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase(Yeast)
Istanbul University

Curated by ChEMBL
LigandPNGBDBM50258298(1-({[5-(Aminosulfonyl)-3-(3-methoxyphenyl)-1H-indo...)
Affinity DataKi:  119nMAssay Description:inhibition of Candida albicans recombinant Nce103 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Istanbul University

Curated by ChEMBL
LigandPNGBDBM50258298(1-({[5-(Aminosulfonyl)-3-(3-methoxyphenyl)-1H-indo...)
Affinity DataKi:  2.84E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant carbonic anhydrase Rv3273 by by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed