BDBM50258204 2-(4-tert-butylphenyl)-4-(4-((5-ethyl-1-methyl-1H-pyrazol-3-yl)methyl)piperazin-1-yl)-1H-benzo[d]imidazole::CHEMBL493185

SMILES CCc1cc(CN2CCN(CC2)c2cccc3[nH]c(nc23)-c2ccc(cc2)C(C)(C)C)nn1C

InChI Key InChIKey=FMNZDRBPLCTEMZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50258204   

TargetGonadotropin-releasing hormone receptor(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50258204(2-(4-tert-butylphenyl)-4-(4-((5-ethyl-1-methyl-1H-...)
Affinity DataIC50: 350nMAssay Description:Displacement of [125I]-(D-Trp6)-GnRH from rat GnRH receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50258204(2-(4-tert-butylphenyl)-4-(4-((5-ethyl-1-methyl-1H-...)
Affinity DataIC50: 43nMAssay Description:Displacement of [125I]-(D-Trp6)-GnRH from human GnRH receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50258204(2-(4-tert-butylphenyl)-4-(4-((5-ethyl-1-methyl-1H-...)
Affinity DataIC50: 7nMAssay Description:Inhibition of GnRH receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed