BDBM50257920 CHEMBL493961::N-(2-(3-(4-methoxyphenyl)-2-oxo-7-(3-(trifluoromethyl)benzylamino)quinoxalin-1(2H)-yl)ethyl)acetamide

SMILES COc1ccc(cc1)-c1nc2ccc(NCc3cccc(c3)C(F)(F)F)cc2n(CCNC(C)=O)c1=O

InChI Key InChIKey=FTECHNJBVQKRNG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50257920   

TargetStearoyl-CoA desaturase(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50257920(N-(2-(3-(4-methoxyphenyl)-2-oxo-7-(3-(trifluoromet...)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of Delta-9-desaturase in human HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Rat)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50257920(N-(2-(3-(4-methoxyphenyl)-2-oxo-7-(3-(trifluoromet...)
Affinity DataIC50: 93nMAssay Description:Inhibition of stearoyl-CoA delta9 desaturase in rat microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50257920(N-(2-(3-(4-methoxyphenyl)-2-oxo-7-(3-(trifluoromet...)
Affinity DataIC50: 33nMAssay Description:Inhibition of stearoyl-CoA delta9 desaturase in human HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed