BDBM50257813 CHEMBL4062291

SMILES CCOC(=O)N1CCC(CC1)NCc1ccc2nc(CC)c(N(C)c3nc(cs3)-c3ccc(Cl)cc3)n2c1

InChI Key InChIKey=SCRFPIGXUGADFV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50257813   

TargetAutotaxin(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM50257813(CHEMBL4062291)
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of glycosylated human ATX using LPC 16:0 as substrate after 30 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetAutotaxin(Rat)
Galapagos

Curated by ChEMBL
LigandPNGBDBM50257813(CHEMBL4062291)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of ATX in rat plasma assessed as reduction in plasma lysophosphatidic acid 18:2 levels after 2 hrs by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetAutotaxin(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM50257813(CHEMBL4062291)
Affinity DataIC50: 9nMAssay Description:Inhibition of glycosylated human ATX using FS-3 as substrate preincubated for 30 mins followed by substrate addition measured after 30 mins by fluore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed