BDBM50257775 CHEMBL4100462

SMILES CCc1nc2ccc(cn2c1N(C)c1nc(cs1)-c1ccc(F)cc1)-c1cccnc1

InChI Key InChIKey=UBYKAUVQNSICFT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50257775   

TargetAutotaxin(Rat)
Galapagos

Curated by ChEMBL
LigandPNGBDBM50257775(CHEMBL4100462)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of ATX in rat plasma assessed as reduction in plasma lysophosphatidic acid 18:2 levels after 2 hrs by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetAutotaxin(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM50257775(CHEMBL4100462)
Affinity DataIC50: 2nMAssay Description:Inhibition of glycosylated human ATX using LPC 16:0 as substrate after 30 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetAutotaxin(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM50257775(CHEMBL4100462)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of glycosylated human ATX using LPC 16:0 as substrate after 30 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed