BDBM50257582 2-(2-aminopyridin-4-yl)-3-(3-chloro-4-fluorophenyl)-1H-pyrrolo[3,2-b]pyridine-5-carbonitrile::CHEMBL522155

SMILES Nc1cc(ccn1)-c1[nH]c2ccc(nc2c1-c1ccc(F)c(Cl)c1)C#N

InChI Key InChIKey=PQCPYSVTVBSQJY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50257582   

TargetHepatocyte growth factor receptor(Human)
Technical University of Darmstadt

Curated by ChEMBL
LigandPNGBDBM50257582(2-(2-aminopyridin-4-yl)-3-(3-chloro-4-fluorophenyl...)
Affinity DataIC50: 130nMAssay Description:Inhibition of GST-tagged human c-Met expressed in SF9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Technical University of Darmstadt

Curated by ChEMBL
LigandPNGBDBM50257582(2-(2-aminopyridin-4-yl)-3-(3-chloro-4-fluorophenyl...)
Affinity DataIC50: 130nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed