BDBM50257496 4-(4-methylpiperazin-1-yl)quinazoline::CHEMBL506969

SMILES CN1CCN(CC1)c2c3ccccc3ncn2

InChI Key InChIKey=RDYFSMILBPHDCN-UHFFFAOYSA-N

Data  1 KI  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50257496   

TargetHuntingtin(Human)
Columbia University

Curated by ChEMBL
LigandPNGBDBM50257496(4-(4-methylpiperazin-1-yl)quinazoline | CHEMBL5069...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Huntingtin protein aggregation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Griffin Discoveries

Curated by ChEMBL
LigandPNGBDBM50257496(4-(4-methylpiperazin-1-yl)quinazoline | CHEMBL5069...)
Affinity DataKi:  328nMAssay Description:Displacement of [3H]histamine from human H4 receptor expressed in HEK cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed