BDBM50257421 (S)-4-Trifluoromethylbenzyl-5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]isatin::CHEMBL521822

SMILES COC[C@@H]1CCCN1S(=O)(=O)c1ccc2N(Cc3ccc(cc3)C(F)(F)F)C(=O)C(=O)c2c1

InChI Key InChIKey=YGIPKOMPEBEYJK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50257421   

TargetCaspase-3(Human)
WestfäLische Wilhelms-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50257421((S)-4-Trifluoromethylbenzyl-5-[1-(2-methoxymethylp...)
Affinity DataIC50: 82nMAssay Description:Inhibition of human recombinant caspase 3More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-7(Human)
WestfäLische Wilhelms-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50257421((S)-4-Trifluoromethylbenzyl-5-[1-(2-methoxymethylp...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant caspase 7More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed